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KMID : 0363220110490010045
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Korean Journal of Dermatology
2011 Volume.49 No. 1 p.45 ~ p.49
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Cronkhite-Canada Syndrome That Developed in a Patient Taking Levothyroxine Sodium after Total Thyroidectomy
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Baek Ji-Hye
Kim Tae-Yoon
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Abstract
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Cronkhite-Canada Syndrome (CCS) is a rare, non-inherited hamartomatous polyposis syndrome. It is characterized by diffuse gastrointestinal polyposis, diarrhea, weight loss and unique ectodermal manifestations such as alopecia, onychodystrophy and cutaneous hyperpigmentation. The etiology of CCS remains unknown, but an autoimmue contribution to the pathogenesis has been postulated. We report here on a 79-year-old male who has been diagnosed with CCS. He had been taking levothyroxine sodium after total thyroidectomy. To the best of our knowledge, this is the first case report of CCS in association with hypothyroidism and supplementation with levothyroxine sodium in the Korean medical literature.
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KEYWORD
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Cronkhite-Canada syndrome, Hypothyroidism, Levothyroxine sodium
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